Setting NFL records is cool - but winning is much cooler in the eyes of Arizona Cardinals QB Jacoby Brissett. In the process of being routed by the San Francisco 49ers in Week 11, Brissett set an NFL record with 47 pass completions today. Brissett, when speaking with reporters after the loss, says he couldn't care less.

The Arizona Cardinals quarterback, who is filling in for the injured Kyler Murray, completed 47 of his 57 pass attempts, setting a new record for completions in a single game. Drew Bledsoe had 45 completions in 1994, and Jared Goff had the same mark in 2019.

Daryl Johnston and Kevin Kugler broke down the San Francisco 49ers massive win over the Arizona Cardinals in Brock Purdy's return.

An injured Kyler Murray, a depleted backfield and really, inconsistent football. It didn’t stop today either in their loss to the San Francisco 49ers in Week 11. Let’s take a look at some key stats that led to the Cardinals' seventh loss of the season:

Expert recap and game analysis of the San Francisco 49ers vs. Arizona Cardinals NFL game from November 16, 2025 on ESPN.

Brock Purdy hit George Kittle for 30-yard TD, extending the San Francisco 49ers lead over the Arizona Cardinals.

Arizona Cardinals safety Budda Baker has been fined by the NFL following Week 11 action. Here’s what led to the league’s decision

The Cardinals signed a familiar wide receiver after Marvin Harrison Jr. was ruled out this week while he recovers from surgery.