The San Francisco 49ers put on a show on the road against the Arizona Cardinals, scoring 41 points on 12 drives, generating three turnovers, and having a 98-yard kickoff return. Are the 49ers back? Let’s get into some overreactions from Week 11.

The San Francisco 49ers dominated their Week 11 matchup as the Arizona Cardinals were exposed once again.

Jacoby Brissett completed an NFL-record 47 passes, but San Francisco's offense rolled in Purdy's first game in weeks.

The San Francisco 49ers finished their Week 11 contest with a 41-22 win over the Arizona Cardinals at State Farm Stadium.

After a frustrating six-week wait to return from injury, 49ers quarterback Brock Purdy didn't take long to get back into a rhythm Sunday, throwing for 200 yards with three touchdowns and no interceptions in a blowout win over the Cardinals.

Brock Purdy threw three touchdown passes in his return from a toe injury, Christian McCaffrey had two rushing touchdowns and a receiving score, and the San Francisco 49ers beat the sloppy Arizona Cardinals 41-22.

The Arizona Cardinals play host to the San Francisco 49ers in Week 11 NFL action. Both teams move into this week hoping to rebound in a massive way

Christian McCaffrey National Football League San Francisco 49ers Top Plays NFL - San Francisco 49ers vs. Arizona Cardinals - 11/16/2025