A research team has discovered an enhanced CRISPR gene-editing system that could enable targeted delivery inside the human ...

Researchers have used modified CRISPR to silence the extra chromosome 21 in Down syndrome cells, showing promising ...

A compact Cas12f nuclease shows high editing efficiency in human cells, with structural insights enabling an engineered variant potentially suited for future AAV‑compatible delivery.

National Institutes of Health (NIH) released the following: A National Institutes of Health (NIH)-funded research team has ...

Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a team of ...

CRISPR-Cas9 has been widely adapted for use in transcriptional modulation and epigenetic engineering with deactivated Cas9 (dCas9) systems to enable CRISPR interference (CRISPRi) and CRISPR activation ...

A major medical milestone took place in May 2025, when doctors at the Children’s Hospital of Philadelphia used CRISPR-based gene editing to treat a child with a rare genetic disorder. Unlike earlier ...

Antibiotic resistance is a global concern that threatens our ability to prevent and treat bacterial infections in humans and animals. To better monitor the emergence and spread of resistance, ...