Cyclic nucleotide-gated cation channels are cation channels controlled from inside the cell by second messengers cAMP and cGMP. They allow for transit of cations sodium, calcium and potassium across ...

Tetrameric cation channels are the largest and best characterized group of ion channels. For this type of ion channel, the ion pathway lies in a pore domain consisting of two transmembrane helices ...

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A lot of people want to be a broadcaster, and a lot of people dream of a career in tennis: What's better than covering and commentating about this beautiful game? But the committment needed to shine ...

Apparent blockage of monovalent cation currents by the permeating blocker Ca²⁺ is a physiologically essential phenomenon relevant to cyclic nucleotide-gated (CNG) channels. The recently determined ...

This is an important study on the sensory roles of Cerebrospinal fluid-contacting neurons (CBF-cn) in mammals. The authors identify PKD2L1 as the predominant pH-sensing channel CBF-cn and show how the ...