If cells in cell cultures grow while being treated with division-suppressing agents, their growth becomes excessive and they permanently lose their ability to divide. However, if the cells are treated ...

Production of recombinant monoclonal antibodies (mAbs) for therapeutic use is a multibillion dollar industry. At present, mammalian cell lines are the workhorses of the biotechnology industry, due to ...

About 100 cells divide every second in our body. A key protein in cell division is a protein kinase termed Plk1, because it activates other proteins involved in this process. Plk1 is also ...

Researchers discovered that a long-misunderstood protein plays a key role in helping chromosomes latch onto the right “tracks ...

When we talk about memories in biology, we tend to focus on the brain and the storage of information in neurons. But there are lots of other memories that persist within our cells. Cells remember ...

The host cell system is a critical determinant of recombinant protein quality and yield, with direct influence on protein folding and post-translational modification factors that shape the ...

A hybrid modeling framework to optimize Chinese hamster ovary cell cultures for monoclonal antibody (mAb) production reduces the number of modeling parameters needed while returning results that ...

Every time a stem cell divides, one daughter cell remains a stem cell while the other takes off on its own developmental journey. But both daughter cells require specific and different cellular ...

If you took high school biology, you probably learned about cell division: a crucial process in all life forms officially called mitosis. For over one hundred years, students have learned that during ...