Discover how therapeutic peptides act as biological messengers to treat disease, improve metabolism, and enhance immune ...

Scientists have developed stable orally available cyclic peptides with a much higher bioavailability than current ones, virtually creating a generation of drugs that can target previously untreatable ...

Drug discovery demands speed and precision, with success often hinging on how quickly teams can move compounds through synthesis, purification, and testing. In this project, flexibility and agility ...

The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism. Bile acids are natural ligands of FXR, which bind to the ...

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat ...

This breakthrough has accelerated peptide drug development across multiple therapeutic areas, including cardiovascular ...

The process of protein identification typically begins with a bottom-up approach, where proteins are enzymatically digested—most commonly with trypsin—into smaller peptides. These peptides are ...