Computer generated 3D model, showing a cross-section of the green RNP spirals, blue hemagglutinin, red neuraminidase, and purple m2 ion channels that constitute the structure of the Influenza A Virus ...

Subclade K (previously known as J.2.4.1) is gaining attention because it appears to be spreading much earlier in the flu ...

Influenza hemagglutinin (HA) glycoprotein is the primary surface antigen targeted by the host immune response and a focus for development of novel vaccines, broadly neutralizing antibodies (bnAbs), ...

One of the challenges faced when developing influenza virus vaccines is the problem of how to protect populations in the face of spreading pandemics. With the advent of air travel, this readily ...

In a recent article published in Immunity, researchers proposed that vaccines targeting the immunosubdominant yet conserved hemagglutinin (HA) stem could trigger broadly neutralizing antibodies (bnAbs ...

Unlike living organisms, to avoid extinction, viruses need to hijack living host machineries to generate new viruses. The devastating respiratory virus, influenza A virus, utilize its hemagglutinin ...

In a recent study published in Emerging Infectious Diseases, researchers performed a quantitative assessment of the age-stratified seroprevalence of hemagglutination inhibition (HAI) antibodies ...

A new study found that a single mutation to the hemagglutinin protein of an H5N1 virus isolated from a dairy worker in Texas this spring switched the protein’s binding specificity from avian- to human ...

Rupert J. Russell, Philip S. Kerry, David J. Stevens, David A. Steinhauer, Stephen R. Martin, Steven J. Gamblin, John J. Skehel Proceedings of the National Academy of ...