P liant Therapeutics has reported interim results from its ongoing Phase I dose escalation trial of PLN-101095, along with ...

Based on the response data, coupled with the supportive IFN- <GAMMA> biomarker data, Pliant plans to accelerate the development of PLN-101095 with the initiation of a Phase 1b indication expansion ...

Interferon-gamma (IFN-γ/IFNG) is a dimerized soluble cytokine and the sole member of the type II interferon class. Originally referred to as macrophage-activating factor, IFN-γ is now recognized as ...

Autoimmune disease such as myocarditis involves an excess of interleukin-12 (IL-12) generating subsequent production of interferon-gamma (IFN-γ). Non-specific immunosuppressive drugs are prescribed ...

To study the use of interferon-gamma release assay (IFN-γ) (IGRAs) as a diagnostic test for tuberculosis (TB)-associated uveitis (TAU). All subjects underwent investigations to rule out underlying ...

T cells have long been studied for their ability to target and eliminate tumor cells. In order for the T cells to do so, the tumors must express antigens not presented by healthy tissues, and the ...

While interferon gamma sounds like an outer space weapon, it's actually a hormone produced by our own bodies, and it holds great promise to repair bones affected by osteoporosis. Researchers now ...

Inflammatory factors derived from adipose tissue have been implicated in mediating insulin resistance in obesity. We sought to identify these using explanted human adipose tissue exposed to innate and ...

This release is available in French. Montreal, March 4th, 2009 – While interferon gamma sounds like an outer space weapon, it's actually a hormone produced by our own bodies, and it holds great ...