The anaphase-promoting complex (APC) initiates exit from mitosis by ubiquitinating A- and B-type cyclins, the activating subunits of cyclin-dependent kinase 1 (Cdk1). Subsequently, the APC has to be ...
The human body is composed of over forty trillion cells. Each of these cells has totally two meters of tightly packaged genomic DNA, the blueprint of life. Recently, there have been many advances in ...