After avoiding an additional punishment, Taylor and the Colts hit the road for a Week 15 matchup against the 10-3 Seattle Seahawks at 4:25 p.m. ET on CBS. Taylor will be taking handoffs from 44-year-old quarterback Philip Rivers, who has not started a game since the 2020 season.

Indianapolis Colts running back Jonathan Taylor runs around the right end for an 11-yard gain. Highlights from the Week 15 matchup between the Baltimore Ravens and the Cincinnati Bengals during the 2025 NFL season.

The RB touch split for Omarion Hampton and Kimani Vidal. Hampton’s 16 touches came on only 23 snaps played, compared to Vidal’s 39 snaps. Neither crossed 10 fantasy points on an offense that’s been on the decline behind an injured offensive line.

Jonathan Taylor has the most rushing yards for a Jacksonville Jaguars opponent this season, but it's not enough as the Indianapolis Colts lose 36-19 in NFL Week 14 . Coming into the game, Taylor led the league with 1,282 rushing yards, and 15 rushing and 17 total TDs. He has 3 touchdowns in five games this season.

Jonathan Taylor and the Colts were dealt a devastating blow when quarterback Daniel Jones suffered a non-contact Achilles injury.

That run-stopping efficiency has been a consistent trend for the Texans throughout the season too. Houston is top-five in the NFL for rushing yards allowed per game (91.7), is top-10 in run-stuff rate (17.9%), and is top-ten in rushing touchdowns allowed (eight).

Adam Koffler's five fantasy football bold predictions for Week 15 of the 2025 NFL season. Expert predictions for Justin Jefferson, Jonathan Taylor, Stefon Diggs, Rico Dowdle, and Isaiah Likely.