The RFC1 G80A polymorphism is closely associated with higher rates of methotrexate-induced toxicity in pediatric acute lymphoblastic leukemia (ALL), according to a study published in the World Journal ...

Risk of isolated central nervous system (CNS) involvement was found to be significantly lower in patients with diffuse large B-cell lymphoma who received high-dose methotrexate vs RCHOP chemotherapy, ...

Please provide your email address to receive an email when new articles are posted on . SAN DIEGO — Split-dose methotrexate had greater efficacy and reduced the need for additional disease-modifying ...

Methotrexate 25mg/mL; soln for IV, IM, intra-arterial, or intrathecal administration after dilution; preservative-free. Non-metastatic osteosarcoma in patients who have undergone surgical resection or ...

A close-up of bad psoriasis on a person’s arm An international consensus establishes methotrexate dosing recommendations for psoriasis treatment and identifies current knowledge gaps on the topic. A ...

A widely used treatment for rheumatoid arthritis may offer an unexpected cardiovascular benefit. Methotrexate has been a staple treatment for rheumatoid arthritis for decades, valued for its ability ...

Exploring Pediatric Oncology Care Practices Influencing the Relationships Among Children, Caregivers, and Health Care Providers: A Multi-Institutional Study From Pakistan HD-MTX dosed at 3,000 mg/m 2 ...

The findings add complexity to questions about the long-term impact of acute lymphoblastic leukemia (ALL) therapy. A new report shows high cumulative doses of intravenous methotrexate can have ...

Randomized, Open-Label, Phase III Study of Tilsotolimod in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced Refractory Melanoma (ILLUMINATE-301) R1 compared induction ...

Please provide your email address to receive an email when new articles are posted on . Low-dose methotrexate did not relieve pain or reduce synovitis in inflammatory knee OA. The findings do not ...