Leon Bellan, associate professor of mechanical and biomedical engineering at Vanderbilt, and his team have developed a novel ...

Naloxone, also known by the brand name Narcan , is one of the most important drugs in the United States' fight against the ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 16 (April 19, 2022), pp. 1-10 (10 pages) Allosteric modulators of G-protein-coupled receptors (GPCRs) ...

We report that opioids from the inflamed colon activate δ-opioid receptors (DOPr) in endosomes of nociceptors. Biopsy samples of inflamed colonic mucosa from patients and mice with colitis released ...

Researchers used emergent MRI technology to understand the impact of prenatal opioid exposure on early brain development and the neural mechanism behind current medications. “Choose life. Choose a job ...

July 11 (UPI) --While scientists have long noted a complex connection between a person's addiction to opiates, or "opioid use disorder," and chronic pain, the brain mechanisms linking the two have ...

AMHERST, Mass (WWLP) – A UMass research team has been developing both a wearable smartwatch sensor called OpiTrack and an app for the detection of opioid cravings. UMass researchers began working on ...

INDIANAPOLIS, March 28, 2023 — There’s been a recent push in the U.S. to make naloxone — a fast-acting opioid antidote — available without a prescription. This medication has saved lives, but it’s ...

In a milestone moment for chronic pain management, Tonix Pharmaceuticals announced on August 15, 2025, that its novel ...