Jacoby Brissett completed an NFL-record 47 passes, but San Francisco's offense rolled in Purdy's first game in weeks.

San Francisco 49ers quarterback Brock Purdy was set to have an "aggressive" practice on Wednesday and the goal this week is for him to start a game for the first time since reinjuring his toe in Week 4.

Before the 49ers and Cardinals face off in their NFC West battle, check out these bold predictions. Can Arizona pull off the upset?

The San Francisco 49ers finished their Week 11 contest with a 41-22 win over the Arizona Cardinals at State Farm Stadium.

The San Francisco 49ers and Arizona Cardinals are two NFL teams that have had rough luck dealing with an avalanche of injuries so far this season.

The Arizona Cardinals‘ attempt to rebound from a divisional blowout was unsuccessful on Sunday, as they were dominated by the San Francisco 49ers to the tune of a 41-16

After a frustrating six-week wait to return from injury, 49ers quarterback Brock Purdy didn't take long to get back into a rhythm Sunday, throwing for 200 yards with three touchdowns and no interceptions in a blowout win over the Cardinals.

Broadcast and streaming information for the San Francisco 49ers Week 11 matchup against the Arizona Cardinals at State Farm Stadium.