This is a preview. Log in through your library . Abstract In budding yeast, phosphate starvation triggers inhibition of the Pho80-Pho85 cyclin--cyclin-dependent kinase (CDK) complex by the CDK ...

The cyclin D1-cyclin-dependent kinase 4 (CDK4) complex is a key regulator of the transition through the G₁ phase of the cell cycle. Among the cyclin/CDKs, CDK4 and cyclin D1 are the most frequently ...

All textbooks describe the cyclin-dependent kinase complex as the one and only/exclusive regulator of the eukaryotic cell cycle. But now University of Groningen scientists have found evidence that a ...

BERKELEY HEIGHTS, N.J., Dec. 5, 2010 (GLOBE NEWSWIRE) -- Cyclacel Pharmaceuticals, Inc. (Nasdaq:CYCC) (Nasdaq:CYCCP) ("Cyclacel" or the "Company"), a biopharmaceutical company developing oral ...

The cells of organisms move through growth stages, duplicating DNA and eventually dividing, and control of that cycle was thought to be understood. The 2001 Nobel Prize in Physiology or Medicine was ...

More than 20 years after the discovery of combination antiretroviral therapy (ART), complete eradication of HIV infection has not yet been achieved. While ART controls viral replication, it is not a ...

DUBLIN--(BUSINESS WIRE)--The "Cyclin-Dependent Kinase (CDK) Inhibitors Therapeutics - Pipeline Analysis 2017" report has been added to Research and Markets' offering. The study analyzed that the CDK ...

Superiority of Oxaliplatin and Fluorouracil-Leucovorin Compared With Either Therapy Alone in Patients With Progressive Colorectal Cancer After Irinotecan and Fluorouracil-Leucovorin: Interim Results ...

Researchers at the Francis Crick Institute have shown that the "pacemaker" controlling yeast cell division lies inside the nucleus rather than outside it, as previously thought. Having the pacemaker ...

All textbooks describe the cyclin-dependent kinase complex as the one and only/exclusive regulator of the eukaryotic cell cycle. But now scientists have found evidence that a metabolic oscillator acts ...