Bacteria independently evolved similar RNA hairpin structures to fix a wasteful flaw in different CRISPR immune systems, ...

Charles Gersbach and his colleagues are pursuing promising CRISPR technologies focused on controlling gene activity rather ...

When scientists discovered how bacteria protect themselves against viral invaders, called phages, in the early 2000s, little did they know they’d stumbled upon a revolutionary tool researchers could ...

Scientists have unveiled two major CRISPR breakthroughs: a ThermoCas9 variant that can distinguish and cut tumor DNA while sparing healthy cells, and a retron-based editing system adapted from E. coli ...

A recent study utilizing cryo-EM advances our understanding of how bacterial immune systems function and reveals new aspects of CRISPR-Cas biology. Researchers at Vilnius University (Lithuania) have ...

Dozens of new discoveries reveal that defenses evolved by bacteria and viruses billions of years ago still define our own ...

The immune system plays a crucial role in fighting tumours and metastases. Consequently, it is decisive to conduct cancer research in mouse models with an immune system that is as natural as possible ...

Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a team of ...

Researchers have used modified CRISPR to silence the extra chromosome 21 in Down syndrome cells, showing promising ...

A principle of DNA synthesis that has dominated biology textbooks for decades could be upended. An enzyme has been discovered ...