See related article at A crisis of communicable diseases is unfolding in North America, just as Canada’s health systems’ responses are being hampered by the dismantling of public health and research ...

A pregnant, primiparous 32-year-old woman at 28 weeks’ gestation presented for a routine prenatal visit. Blood work showed thrombocytopenia with platelet count of 60 (reference range 130–380) × 109/L.

Iron deficiency and iron deficiency anemia are common during pregnancy and are associated with adverse outcomes Prenatal iron deficiency occurs in more than 30% of pregnancies in Canada. 1 It has been ...

KEY POINTS Genitourinary syndrome of menopause (GSM) is common and can be treated with over-the-counter vaginal lubricants or supplementation with vaginal estrogen. Vaginal energy devices (such as CO2 ...

A meta-analysis of 20 000 people from the general population who were patch tested confirmed a 20% prevalence of contact allergy, with nickel being the most common allergen (11.4%). 1 Prevalence is ...

KEY POINTS Multifactorial early-pregnancy screening for preeclampsia can identify most patients at risk, particularly of early-onset, severe disease. Prophylaxis with acetylsalicylic acid (ASA) can ...

Randomized clinical trials play a pivotal role in answering questions about the superiority of competing treatments. They are initiated not because a particular investigator is unsure of the treatment ...

As a specialist in internal medicine, Brian Harley explores the intricate terrain of the human body. But as a writer and amateur historian, he turns his attention to the rugged landscape of the place ...

Figure 1: (A) Electrocardiogram of a 54-year-old man with chest pain. The QRS complex was in QS pattern in lead V 1, the delta wave was positive in leads I, II and aVF (dashed arrows), and ST segment ...

Background: In Canada, many patients face substantial out-of-pocket costs for prescription medication, which may affect their ability to take their medications as prescribed. We sought to conduct a ...

Box 1: Evidence used in this review We drew on the international guideline on the management of polycystic ovarian syndrome (PCOS) published by the European Society of Human Reproduction and ...