The pontiff's condition is touch-and-go, given his age, fragility and pre-existing lung disease, according to doctors.
The Vatican No. 2, Cardinal Pietro Parolin, will lead the first prayer Monday. Francis, who has double pneumonia and is in the early stages of kidney insufficiency, was awake and in good spirits Monday.
The Vatican has laws to ensure the transfer of power when a pope dies or resigns, but they don't apply if he is sick.
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