The San Francisco 49ers resume their quest for the No. 1 seed in the NFC West - yes, seriously - by facing the Tennessee Titans, who are tied for the worst record in the NFL.

The San Francisco 49ers have placed wide receiver Brandon Aiyuk on the reserve/left squad list, ending his 2025 season before ...

The San Francisco 49ers on Saturday placed Brandon Aiyuk on the reserve/left squad list, ending his 2025 season and likely ...

The San Francisco 49ers have placed receiver Brandon Aiyuk on the reserve/left squad list, making him ineligible to return ...

USA Today's NFL experts make their picks for a Week 15 showdown between the San Francisco 49ers and Tennessee Titans ...

The Steelers might need to work a trade for their starting quarterback next season and here are three who could be out there.

The 49ers placed Aiyuk (knee) on the reserve/left squad list Saturday, Matt Barrows of The Athletic reports.

With just four games left in the 2025 NFL season, the Cleveland Browns appear to be at a crossroads with their quarterback ...

John looks at QB fantasy football playoffs strength of schedules, the best/worst quarterback matchups for 2025 fantasy football playoffs (Weeks 15, 16, 17).

Our experts' predictions are in for Tennessee Titans vs. San Francisco 49ers on Sunday. Here's who our experts are picking to ...

Jaguars safety Eric Murray admitted he was uncertain if he would return this season after his October neck injury.

Which high-profile rookies have impressed? Disappointed? With less than a month remaining in the regular season, Bucky Brooks ...