Perturbations in intracellular Ca homeostasis, produced by Pb at low concentrations, may be an unifying hypothesis to explain Pb toxicity at the cellular level. Such perturbations may place the ...
Precise Ca cycling through the sarcoplasmic reticulum (SR), a Ca storage organelle, is critical for proper cardiac muscle function. This cycling initially involves SR release of Ca via the ryanodine ...
Taking out the garbage is a crucial step in housecleaning. Similarly, autophagy is the body’s first-line of defense against the buildup up of toxic substances, degrading old organelles and proteins to ...
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