NANOG has multifaceted roles in naïve hESCs, orchestrating transcriptional, metabolic, and epigenetic signatures in naïve hESCs, and governing acetyl-CoA synthesis, bivalent metabolism, and redox ...

The endocannabinoid system is found throughout the brain and body and plays a key role in everything from memory and learning ...

The gut lining of the human body is just one cell thick, not because it’s weak, but because it has to absorb nutrients with ...

Gut microbiota capable of metabolizing uric acid and purines may play a key role in reducing gout diagnoses, and although the ...

Diesel exhaust particles can disturb the function of human brain immune cells, known as microglia, according to a recent ...

This first-in-class ASO replicates the protective effects of naturally occurring CD33 loss-of-function variants, which are associated with increased resilience to neurodegenerative disease, reduced ...

Background Eosinophilic oesophagitis (EoE) is a chronic allergic disease characterised by oesophageal epithelial remodelling, barrier dysfunction and inflammation. The transcription factor forkhead ...

Scientists have developed a new molecule that breaks down beta-amyloid plaques by binding to excess copper in the brain. The ...

Diesel exhaust particles can disturb the function of human brain immune cells, known as microglia, according to a recent study led by the University ...

Foralumab is the only fully human anti-CD3 monoclonal antibody (mAb) currently in clinical development. Immunomodulation by intranasal foralumab represents a novel avenue for the treatment of ...

New research published in the journal Nature suggests that modest doses of lithium orotate may prevent or even reverse ...