Jacoby Brissett completed an NFL-record 47 passes, but San Francisco's offense rolled in Purdy's first game in weeks.

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are ...

Brock Purdy’s return went perfectly on Sunday afternoon. The San Francisco 49ers quarterback started after missing six ...

The Cardinals quarterback completed 47 passes against the San Francisco 49ers — a new NFL record. Brissett went 47-of-57 for ...

Full-strength offense explodes, showcasing dominant Purdy, McCaffrey, and Kittle. Niners dominate, extending their bizarre ...

The NFL season continues in Week 11 when the San Francisco 49ers host the Arizona Cardinals on Sunday. Start time, how to ...

The San Francisco 49ers face the Arizona Cardinals in Week 11 of the NFL season on Sunday at State Farm Stadium.

The San Francisco 49ers and Arizona Cardinals face off in Week 11 of the NFL today. Here's where to watch and start time ...

The San Francisco 49ers (6-4) visit the Arizona Cardinals (3-6) Sunday in Week 11. Kickoff from State Farm Stadium in ...

Call Sunday’s Niners-Cardinals showdown the Battle of Wounded Knee… and Leg, and Shoulder, and Feet, and even Appendixes. You ...

On the 49ers first touchdown of the game, linebacker Akeem Davis-Gaither was matched up with star tight end George Kittle in ...