Jacoby Brissett completed an NFL-record 47 passes, but San Francisco's offense rolled in Purdy's first game in weeks.

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are ...

Brock Purdy’s return went perfectly on Sunday afternoon. The San Francisco 49ers quarterback started after missing six ...

The Cardinals quarterback completed 47 passes against the San Francisco 49ers — a new NFL record. Brissett went 47-of-57 for ...

The San Francisco 49ers and Arizona Cardinals face off in Week 11 of the NFL today. Here's where to watch and start time ...

The San Francisco 49ers (6-4) visit the Arizona Cardinals (3-6) Sunday in Week 11. Kickoff from State Farm Stadium in ...

Call Sunday’s Niners-Cardinals showdown the Battle of Wounded Knee… and Leg, and Shoulder, and Feet, and even Appendixes. You ...

On the 49ers first touchdown of the game, linebacker Akeem Davis-Gaither was matched up with star tight end George Kittle in ...

The Cardinals' Week 11 game against the 49ers will basically only get coverage in the two teams' home viewing markets.

An NFL insider has revealed a clear update on whether or not the San Francisco 49ers will make a quarterback trade.

What's the Arizona Cardinals vs San Francisco 49ers score? Follow our live score updates for latest news, highlights, ...