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NFL Week 11: 49ers vs Cardinals Betting Preview & Predictions

Brock Purdy returns to the San Francisco 49ers lineup in Week 12. Can he lead the Niners past the Arizona Cardinals in a crucial NFC West showdown on Sunday?

· 1d

49ers vs. Cardinals prediction, pick, odds for Sunday's NFL Week 11 game

· 15h · on MSN

49ers vs. Cardinals: Where to watch NFL Week 11, betting odds, score prediction, sportsbook promos, SGP picks

Cards Wire · 15h

What TV channel is Cardinals vs. 49ers on today? Time, TV schedule for NFL Week 11 game

The Arizona Cardinals are back in action in Week 11 and face the San Francisco 49ers for the second time this season.

· 21h

NFL Week 11 storylines: Divisional showdowns, playoff previews lead tremendous Sunday slate

· 6h

Kyle Shanahan has a couple concerning injury updates after 49ers big Week 11 win

Cards Wire · 1d

Arizona Cardinals, San Francisco 49ers announce uniform combinations for Week 11

The Cardinals will, for the second and final time this season, wear their alternate all-black uniforms with their black helmets.

· 20h

Where to watch 49ers vs. Cardinals free live stream today (11/16/25) without Streameast

· 7h

Seahawks vs. Rams live updates: NFL Week 11 game score, highlights

49ers top Cardinals in Brock Purdys return

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· 6h

Brock Purdy, George Kittle Make 49ers History During Blowout Over Cardinals

Along the way to the 49ers’ Week 11 win, Kittle found his way into the team’s record book, as he joined Terrell Owens and Jerry Rice as the only three players in the history of the franchise to record 500 catches and 50 touchdowns.

USA TODAY Touchdown Wire on MSN · 5h

George Kittle enters elite company in 49ers history with big game vs. Cardinals

Arizona Sports · 9h

Valley native Brock Purdy throws touchdown to Kittle vs. Cardinals to move up 49ers’ record ladder

7hon MSN

Ex-Patriots QB sets new NFL record in loss to 49ers

The Cardinals quarterback completed 47 passes against the San Francisco 49ers — a new NFL record. Brissett went 47-of-57 for 452 yards, two touchdowns and two interceptions. The 49ers, though, were too much for the Cardinals as they fell,

How Mac Jones joined Jeff Garcia, Steve Young in 49ers record book vs. Rams

Mac Jones joined Jeff Garcia and Steve Young in the 49ers’ record book during Sunday’s 42-26 loss to the Los Angeles Rams.

7hon MSN

Jacoby Brissett Sets NFL Record for Completions in Cardinals' loss to 49ers

Arizona didn't prevail in Week 11, but their veteran quarterback still managed to turn in a historic outing against San Francisco.

Arizona Sports

Emari Demercado exits Cardinals-49ers with ankle injury

Cardinals running back Emari Demercado exited the second quarter of his team's game against the San Francisco 49ers with an ankle injury.

16don MSN

49ers Announce QB Starter for Week 9 Game Against Giants

The San Francisco 49ers are one of the most banged teams in the NFL right now, with a question mark at quarterback every week.