The most notable is the team franchise record set by the Cardinals for most penalties, with 17 for a total of 130 yards, ...

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

Jacoby Brissett completed an NFL-record 47 passes, but San Francisco's offense rolled in Purdy's first game in weeks.

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are ...

The San Francisco 49ers entered Sunday in Week 11 with a healthy team, at least in terms of players on the roster.

On the 49ers first touchdown of the game, linebacker Akeem Davis-Gaither was matched up with star tight end George Kittle in one-on-one coverage. With Kittle running a slot fade, Davis-Gaither had no ...

The Arizona Cardinals set a new franchise record during a loss to the San Francisco 49ers on Sunday, but not the good kind.

I don’t know any other running backs that can do that, to be honest,” Brock Purdy said of Christian McCaffrey’s touchdown ...

The San Francisco 49ers took full advantage of an inferior opponent Sunday, marking Brock Purdy's return to action in a 41-22 ...

The Cardinals have now lost seven of their last eight, including two straight blowouts to divisional opponents.

The San Francisco 49ers picked off Arizona's Jacoby Brissett twice, a defensive counter to the QB's NFL record 47 completions ...

The San Francisco 49ers finished their Week 11 contest with a 41-22 win over the Arizona Cardinals at State Farm Stadium.