The most notable is the team franchise record set by the Cardinals for most penalties, with 17 for a total of 130 yards, ...

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

Jacoby Brissett completed an NFL-record 47 passes, but San Francisco's offense rolled in Purdy's first game in weeks.

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are ...

The San Francisco 49ers entered Sunday in Week 11 with a healthy team, at least in terms of players on the roster.

On the 49ers first touchdown of the game, linebacker Akeem Davis-Gaither was matched up with star tight end George Kittle in ...

With these two crucial weapons back on the gridiron, 49ers fans will have to like their team's chances this weekend. The ...

The San Francisco 49ers and Arizona Cardinals are two NFL teams that have had rough luck dealing with an avalanche of ...

San Francisco 49ers quarterback Brock Purdy was set to have an "aggressive" practice on Wednesday and the goal this week is ...

For the last six weeks, San Francisco's operated without their top quarterback. Head coach Kyle Shanahan says that changes in ...

The Arizona Cardinals set a new franchise record during a loss to the San Francisco 49ers on Sunday, but not the good kind.