Oct 6, 2024; Santa Clara, California, USA; San Francisco 49ers tight end George Kittle (85) gestures after a catch against the Arizona Cardinals during the fourth quarter at Levi's Stadium. Mandatory Credit: Darren Yamashita-Imagn Images / Darren Yamashita-Imagn Images

There is no sugarcoating it, the Arizona Cardinals are in a total free fall. The early stages of this brutal skid were defined by heartbreaking losses, like blown fourth-quarter leads to the Tennessee Titans and the San Francisco 49ers.

Bam Knight is active for the Arizona Cardinals' Week 11 game against the San Francisco 49ers and will likely lead the backfield, as he has recently.

Can the Arizona Cardinals upset the 49ers in Week 11? Explore the keys to victory, including Michael Wilson stepping up, Cody Simon’s defensive leadership, and Jonathan Gannon’s aggressive game plan.

The San Francisco 49ers are already without Fred Warner, and they may have lost another linebacker early against the Arizona Cardinals on Sunday.

Cardinals running back Emari Demercado exited the second quarter of his team's game against the San Francisco 49ers with an ankle injury.

Kris Boyd, who played with the Cardinals in 2023 and is currently with the New York Jets, was shot early Nov 16 in Midtown Manhattan, police said.

With the activation of linebacker BJ Ojulari from PUP Saturday and the addition of linebacker Mack Wilson Sr. to IR, the Cardinals now have 13 players placed on IR since the cut to 53, three on IR prior to the cut to 53 and one, cornerback Sean Murphy-Bunting, on reserve/non-football injury, also done prior to the reduction to 53.

Brock Purdy threw a touchdown to George Kittle early in his second start as a pro in Arizona to move up the 49ers' record books as a duo.

San Francisco 49ers wide receiver Skyy Moore opens the game against the Arizona Cardinals with a 98-yard kick return.