Head coach Kyle Shanahan of the San Francisco 49ers looks on during warmups before the game against the Arizona Cardinals at ...

Head coach Kyle Shanahan said afterward that the 39-year-old may have suffered the type of injury that could lead to him ...

QB Brock Purdy relished his "special" return to the field in his hometown as San Francisco blew out the Arizona Cardinals ...

After the San Francisco 49ers rolled past the Arizona Cardinals, Kyle Shanahan provided several key injury updates.

I don’t know any other running backs that can do that, to be honest,” Brock Purdy said of Christian McCaffrey’s touchdown ...

49ers head coach Kyle Shanahan, during an appearance on NBC Sports 49ers Talk, had some very high praise for Pearsall amid ...

Let all that nonsense about a quarterback controversy — which was being pushed by even reputable NFL voices — be put to bed.

The Arizona Cardinals and San Francisco 49ers revealed their final inactives report for Week 11 - who's in, who's out?

Mac Jones filled in well as the 49ers' starting quarterback while Brock Pirdy has been out, but now he's headed back to the ...

A big stretch of games begins for the San Francisco 49ers on Sunday in Arizona against the Cardinals. Here's how to watch ...

The 49ers and Saints, to completely different results, revealed the best way to stop the Rams' vaunted pass rush. It's called ...

Shanahan breaks down the latest 49ers injury updates after the Week 11 win over the Cardinals, including key statuses for ...