Glendale, AZ -- The 49ers just blew out the Arizona Cardinals 41-22. Granted, the Cardinals got blown out last week too and ...

An injured Kyler Murray, a depleted backfield and really, inconsistent football. It didn’t stop today either in their loss to ...

The San Francisco 49ers picked off Arizona's Jacoby Brissett twice, a defensive counter to the QB's NFL record 47 completions ...

» Not only did the Niners’ tight end catch a touchdown of his own, but he was instrumental on the 49ers’ third touchdown of ...

I don’t know any other running backs that can do that, to be honest,” Brock Purdy said of Christian McCaffrey’s touchdown ...

San Francisco 49ers QB Brock Purdy dispensed with questions over his health and simultaneously silenced debate over Mac Jones ...

Brock Purdy passed for 200 yards and three touchdowns in his first game since Sept. 28, Christian McCaffrey scored three ...

After a frustrating six-week wait to return from injury, 49ers quarterback Brock Purdy didn't take long to get back into a ...

Jacoby Brissett completed an NFL-record 47 passes, but San Francisco's offense rolled in Purdy's first game in weeks.

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

The Arizona Cardinals quarterback, who is filling in for the injured Kyler Murray, completed 47 of his 57 pass attempts, ...

San Francisco 49ers' QB Brock Purdy discusses his return from injury and three touchdown performance against the Arizona Cardinals.