San Francisco 49ers running back Christian McCaffrey scores his tenth touchdown of the 2025 NFL season, and second of the game, on a 9-yard reception from quarterback Brock Purdy against the Arizona ...

Sunday marks the start of a crucial stretch of games for the San Francisco 49ers, who will visit the Arizona Cardinals to begin that four-game journey. The 49ers are in Arizona before ...

The San Francisco 49ers open the game with a 98-yard kick return and running back Christian McCaffrey caps off the drive on ...

San Francisco 49ers RB Christian McCaffrey muscled his way into the end zone from one yard out during the 49ers Week 11 ...

San Francisco 49ers WR Skyy Moore sped past the Cardinals coverage unit with a 98-yard kickoff return to open the Week 11 ...

View the San Francisco 49ers vs. Arizona Cardinals game played on November 16, 2025. Box score, stats, odds, highlights, play-by-play, social & more ...