Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are ...

Expert recap and game analysis of the San Francisco 49ers vs. Arizona Cardinals NFL game from November 16, 2025 on ESPN.

Jacoby Brissett completed an NFL-record 47 passes, but San Francisco's offense rolled in Purdy's first game in weeks.

Brock Purdy’s return went perfectly on Sunday afternoon. The San Francisco 49ers quarterback started after missing six ...

Arizona didn't prevail in Week 11, but their veteran quarterback still managed to turn in a historic outing against San ...

The Cardinals quarterback completed 47 passes against the San Francisco 49ers — a new NFL record. Brissett went 47-of-57 for ...

Full-strength offense explodes, showcasing dominant Purdy, McCaffrey, and Kittle. Niners dominate, extending their bizarre ...

Daryl Johnston and Kevin Kugler broke down the San Francisco 49ers massive win over the Arizona Cardinals in Brock Purdy's ...

The NFL season continues in Week 11 when the San Francisco 49ers host the Arizona Cardinals on Sunday. Start time, how to ...

The San Francisco 49ers face the Arizona Cardinals in Week 11 of the NFL season on Sunday at State Farm Stadium.

The San Francisco 49ers and Arizona Cardinals face off in Week 11 of the NFL today. Here's where to watch and start time ...